CD305 (LAIR1) Antigen

CD305, also called LAIR1 (Leucocyte-associated Ig-like receptor 1), is a 31 kDa type 1 transmembrane molecule with a single N terminal extracellular Ig superfamily C2 domain. The extracellular domain contains one N-glycosylation site. CD305 is expressed on the majority of lymphocytes, NK cells, monocytes, dendritic cells and naïve B cells. It inhibits cell cytotoxicity, cell activation, proliferation and differentiation by phosphorylation of its cytoplasmic ITIM motifs.

 Clone: NKTA255  Isotype: IgG1 Mouse

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Technical Documents