IL-4 Antigen

Interleukin-4 (IL-4) is a monomeric 20 kDa predominantly produced by activated T lymphocytes of the Th2 phenotype, by mast cells and by some antigen-presenting cells. Together with IL-2, IL-4 is an autocrine growth factor for activated T cells and for cytotoxic T cell precursors. IL-4 is a major factor involved in the activation of resting B lymphocytes. Together with IL-13, IL-4 induces isotype switch towards IgE and IgG1 isotypes. Activated CD4+ T cells of the Th1 phenotype produce predominantly IL-2 and Interferon γ, whereas CD4+ T cells of the Th2 phenotype produce IL-4, IL-5, IL6 and IL-10.


Clone: 4D9  Isotype: IgG1 Mouse

The 4D9-PE-conjugated antibody is optimized for flow cytometric detection of intracellular IL-4 in stimulated peripheral mononuclear cells (PBMC) after permeabilizing with formaldehyde / saponin-based IntraPrep Permeabilization Reagent.

Clone: MP4-25D2 Isotype: IgG1 Rat


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Product Line Specifications

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The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Technical Documents